Is 2-Heptanol safe in cosmetics?
2-Heptanol has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
2-Heptanol
Also known as: 3-01-00-01685, BRN 1719088, EINECS 208-844-3, FEMA No. 3288, Heptyl alcohol, sec- (+2 more)
2-Heptanol (CAS 543-49-7) is a cosmetic cosmetic ingredient functioning as Flavouring and nutrient; Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 543-49-7 →
Auto-generated CPSR Part A draft with source citations
Function
Flavouring and nutrient; Fragrance
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
heptan-2-ol
InChIKey
CETWDUZRCINIHU-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically restricted by FDA; RIFM-assessed as safe
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2-Heptanol.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Short-term Exposure Effects
The substance is severely irritating to the eyes. The substance is irritating to the respiratory tract. The substance is mildly irritating to the skin. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis.
Long-term Exposure Effects
The substance defats the skin, which may cause dryness or cracking.
Routes of Exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
ICSC Safety Card
1083
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Regulatory (2)
JECFA Number
284
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
2-HEPTANOL | 1998 | No safety concern at current levels of intake when used as a flavouring agent | TRS 891-JECFA 51/59 | FAS 42-JECFA 51/235
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for 2-Heptanol.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
3-01-00-01685
BRN 1719088
EINECS 208-844-3
FEMA No. 3288
Heptyl alcohol, sec-
UNII-E12FIG07JK
(±)-2-Heptanol
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
2-HEPTANOL
ChEMBL ID
CHEMBL449522
Frequently Asked Questions
Is 2-Heptanol allowed in the EU?
2-Heptanol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Heptanol do in cosmetics?
2-Heptanol functions as: Flavouring and nutrient; Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 543-49-7.
Is 2-Heptanol used outside cosmetics?
2-Heptanol also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 2-Heptanol compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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