Good Cosmetic Ingredient GHS Classified

2-Heptanol

CAS Number
543-49-7
Function
Flavouring and nutrient; Fragrance
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically restricted by FDA; RIFM-assessed as safe

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is severely irritating to the eyes. The substance is irritating to the respiratory tract. The substance is mildly irritating to the skin. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis.
Long-term Exposure Effects
The substance defats the skin, which may cause dryness or cracking.
Routes of Exposure
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Expert Verdict

No chromophore indicates no phototoxicity or photoallergenicity concern. Not genotoxic. Weight of evidence from structural analysis, animal and human studies confirms safety for skin sensitization.

⚠️
Concern Level: Low

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is 2-Heptanol safe in cosmetics?

No chromophore indicates no phototoxicity or photoallergenicity concern. Not genotoxic. Weight of evidence from structural analysis, animal and human studies confirms safety for skin sensitization. The EU classifies 2-Heptanol as "permitted". Safety rating: GOOD.

Is 2-Heptanol allowed in the EU?

2-Heptanol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 2-Heptanol do in cosmetics?

2-Heptanol functions as: Flavouring and nutrient; Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 543-49-7.

What is the Margin of Safety for 2-Heptanol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check 2-Heptanol compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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