Is 2-Methoxy-4-Methoxymethyl-Phenol safe in cosmetics?
2-Methoxy-4-Methoxymethyl-Phenol has a safety rating of "GOOD" in our database. EU status: prohibited. US status: permitted.
Good
Cosmetic Ingredient
2-Methoxy-4-Methoxymethyl-Phenol
Also known as: EINECS 226-882-9
INCI: 2-METHOXY-4-METHOXYMETHYL-PHENOL
2-Methoxy-4-Methoxymethyl-Phenol (CAS 5533-03-9) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 5533-03-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
2-Methoxy-4-Methoxymethyl-Phenol is prohibited in EU cosmetics but has active industrial GHS classifications.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word
Function
Fragrance (perfuming)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-methoxy-4-(methoxymethyl)phenol
InChIKey
USDDPDQEVLAOBO-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Permitted — no FDA cosmetic prohibition
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2-Methoxy-4-Methoxymethyl-Phenol.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for 2-Methoxy-4-Methoxymethyl-Phenol.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
EINECS 226-882-9
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 2-Methoxy-4-Methoxymethyl-Phenol allowed in the EU?
2-Methoxy-4-Methoxymethyl-Phenol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Methoxy-4-Methoxymethyl-Phenol do in cosmetics?
2-Methoxy-4-Methoxymethyl-Phenol functions as: Fragrance (perfuming). It is classified as a cosmetic ingredient in our database. CAS number: 5533-03-9.
Is 2-Methoxy-4-Methoxymethyl-Phenol used outside cosmetics?
2-Methoxy-4-Methoxymethyl-Phenol also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does 2-Methoxy-4-Methoxymethyl-Phenol have different safety status in cosmetics vs industrial chemicals?
2-Methoxy-4-Methoxymethyl-Phenol is prohibited in EU cosmetics but has active industrial GHS classifications.
Compliance Tools
Check 2-Methoxy-4-Methoxymethyl-Phenol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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