2-Methoxy-p-Phenylenediamine Sulfate

INCI: 2-METHOXY-P-PHENYLENEDIAMINE SULFATE

CAS Number
Sulfate salt of 2-methoxy-p-phenylenediamine — base CAS referenced in SCCS opinions; CosIng-registered
Function
Hair dye (oxidative hair coloring)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Permitted for hair dye use; coal-tar hair dyes carry the statutory caution labeling requirement under FD&C Act §601(a); not on FDA's prohibited list

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Mandatory patch test warning required; must comply with concentration limits and mixing ratios; EU requires label statement 'Can cause an allergic reaction'; professional-use considerations apply

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Concern Level: High

Frequently Asked Questions

Is 2-Methoxy-p-Phenylenediamine Sulfate safe in cosmetics?

Mandatory patch test warning required; must comply with concentration limits and mixing ratios; EU requires label statement 'Can cause an allergic reaction'; professional-use considerations apply The EU classifies 2-Methoxy-p-Phenylenediamine Sulfate as "restricted". Safety rating: MODERATE.

Is 2-Methoxy-p-Phenylenediamine Sulfate allowed in the EU?

2-Methoxy-p-Phenylenediamine Sulfate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does 2-Methoxy-p-Phenylenediamine Sulfate do in cosmetics?

2-Methoxy-p-Phenylenediamine Sulfate functions as: Hair dye (oxidative hair coloring). It is classified as a cosmetic ingredient in our database. CAS number: Sulfate salt of 2-methoxy-p-phenylenediamine — base CAS referenced in SCCS opinions; CosIng-registered.

What is the Margin of Safety for 2-Methoxy-p-Phenylenediamine Sulfate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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