2-Methoxymethyl-P-Phenylenediamine Sulfate

INCI: 2-METHOXYMETHYL-P-PHENYLENEDIAMINE SULFATE

CAS Number
337906-37-3 (sulfate salt of ME-PPD)
Function
Hair dyeing (water-soluble salt form of ME-PPD)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Same as free base โ€” FD&C Act ยง601 hair dye exemption applies

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Prohibited in EU due to sensitization risk; permitted in US under hair dye exemption with mandatory cross-reactivity warnings for PPD-sensitized individuals.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is 2-Methoxymethyl-P-Phenylenediamine Sulfate safe in cosmetics?

Prohibited in EU due to sensitization risk; permitted in US under hair dye exemption with mandatory cross-reactivity warnings for PPD-sensitized individuals. The EU classifies 2-Methoxymethyl-P-Phenylenediamine Sulfate as "prohibited". Safety rating: GOOD.

Is 2-Methoxymethyl-P-Phenylenediamine Sulfate allowed in the EU?

2-Methoxymethyl-P-Phenylenediamine Sulfate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 2-Methoxymethyl-P-Phenylenediamine Sulfate do in cosmetics?

2-Methoxymethyl-P-Phenylenediamine Sulfate functions as: Hair dyeing (water-soluble salt form of ME-PPD). It is classified as a cosmetic ingredient in our database. CAS number: 337906-37-3 (sulfate salt of ME-PPD).

What is the Margin of Safety for 2-Methoxymethyl-P-Phenylenediamine Sulfate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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