2-Methylbutyric Acid

INCI: 2-METHYLBUTYRIC ACID

CAS Number
116-53-0
Function
Fragrance ingredient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FEMA GRAS; no FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Corrosive/irritant at high concentrations (pH-dependent); must be used at appropriate dilution; strong odor

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is 2-Methylbutyric Acid safe in cosmetics?

Corrosive/irritant at high concentrations (pH-dependent); must be used at appropriate dilution; strong odor The EU classifies 2-Methylbutyric Acid as "permitted". Safety rating: GOOD.

Is 2-Methylbutyric Acid allowed in the EU?

2-Methylbutyric Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 2-Methylbutyric Acid do in cosmetics?

2-Methylbutyric Acid functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 116-53-0.

What is the Margin of Safety for 2-Methylbutyric Acid?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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