Is 2,2'-Methylenebis-4-Aminophenol HCl safe in cosmetics?
2,2'-Methylenebis-4-Aminophenol HCl has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
2,2'-Methylenebis-4-Aminophenol HCl
INCI: 2,2'-METHYLENEBIS-4-AMINOPHENOL HCL (COLIPA N° A155)
2,2'-Methylenebis-4-Aminophenol HCl (CAS 27311-52-0 (dihydrochloride salt)) is a cosmetic cosmetic ingredient functioning as Hair dyeing - oxidative and non-oxidative hair dye. EU Regulation 1223/2009 status: restricted, max 2.0%. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 27311-52-0 (dihydrochloride salt) →
Auto-generated CPSR Part A draft with source citations
Function
Hair dyeing - oxidative and non-oxidative hair dye
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
EU Max Conc.
2.0%
US US Status
permitted
US Notes
Coal tar hair dye exemption; labeling and patch test requirements apply
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2,2'-Methylenebis-4-Aminophenol HCl.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for 2,2'-Methylenebis-4-Aminophenol HCl.
Regulatory Flags
potential-allergen
Frequently Asked Questions
Is 2,2'-Methylenebis-4-Aminophenol HCl allowed in the EU?
2,2'-Methylenebis-4-Aminophenol HCl EU regulatory status: restricted. Maximum allowed concentration: 2.0%. This is based on EU Regulation 1223/2009 and its amendments.
What does 2,2'-Methylenebis-4-Aminophenol HCl do in cosmetics?
2,2'-Methylenebis-4-Aminophenol HCl functions as: Hair dyeing - oxidative and non-oxidative hair dye. It is classified as a cosmetic ingredient in our database. CAS number: 27311-52-0 (dihydrochloride salt).
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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2,2'-METHYLENEBIS-4-AMINOPHENOL
Good
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Hair Dyeing
2,2'-Methylenebis 4-Aminophenol
Moderate
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Hair dyeing - oxidation hair colorant...
2,2'-Thiobis(4-Chlorophenol)
Poor
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Antimicrobial / antifungal agent
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