Is 2,4,6-Trimethyl-3-cyclohexenecarbaldehyde safe in cosmetics?
2,4,6-Trimethyl-3-cyclohexenecarbaldehyde has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
2,4,6-Trimethyl-3-cyclohexenecarbaldehyde
Also known as: 2,4,6-Trimethylcyclohex-3-ene-1-carbaldehyde, Vertonal, 3-Cyclohexene-1-carboxaldehyde, 2,4,6-trimethyl-, 3-Cyclohexene-1-carboxaldehyde, 2,4,6-trimethyl-, 2,4,6-Trimethyl-3-cyclohexene-1-carbaldehyde (+10 more)
INCI: 2,4,6-TRIMETHYL-3-CYCLOHEXENECARBALDEHYDE
2,4,6-Trimethyl-3-cyclohexenecarbaldehyde (CAS 1423-46-7) is a cosmetic cosmetic ingredient functioning as Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 1423-46-7 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
2,4,6-Trimethyl-3-cyclohexenecarbaldehyde is classified GHS Danger (H315, H317, H319, H334, H400, H412) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Fragrance
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2,4,6-trimethylcyclohex-3-ene-1-carbaldehyde
InChIKey
YJSUCBQWLKRPDL-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted in cosmetics as fragrance component
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2,4,6-Trimethyl-3-cyclohexenecarbaldehyde.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
Expert Verdict
Expert safety assessment and concern-level summary for 2,4,6-Trimethyl-3-cyclohexenecarbaldehyde.
Regulatory Flags
potential-allergen
fragrance-component
epa_safer_alternative
ifra_fragrance
Known Synonyms
2,4,6-Trimethylcyclohex-3-ene-1-carbaldehyde
Vertonal
3-Cyclohexene-1-carboxaldehyde, 2,4,6-trimethyl-
3-Cyclohexene-1-carboxaldehyde, 2,4,6-trimethyl-
2,4,6-Trimethyl-3-cyclohexene-1-carbaldehyde
2,4,6-Trimethyl-3-cyclohexenylcarbaldehyde
2,4,6-Trimethyl-3-cyclohexenylcarboxaldehyde
2,4,6-trimethylcyclohex-3-enecarbaldehyde
CYCLOHEX-3-ENE-1-CARBOXALDEHYDE, 2,4,6-TRIMETHYL-
3-Cyclohexene-1-carboxaldehyde, 2,4,6-trimethyl
EINECS 215-833-7
NSC 406736
2,4,6-Trimethyl-3-cyclohexene-1-carboxaldehyde
UNII-3RP77Q40LC
Isocyclocitral Tech
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
SCIL (9/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3186544
Frequently Asked Questions
Is 2,4,6-Trimethyl-3-cyclohexenecarbaldehyde allowed in the EU?
2,4,6-Trimethyl-3-cyclohexenecarbaldehyde EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2,4,6-Trimethyl-3-cyclohexenecarbaldehyde do in cosmetics?
2,4,6-Trimethyl-3-cyclohexenecarbaldehyde functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 1423-46-7.
Is 2,4,6-Trimethyl-3-cyclohexenecarbaldehyde used outside cosmetics?
2,4,6-Trimethyl-3-cyclohexenecarbaldehyde also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does 2,4,6-Trimethyl-3-cyclohexenecarbaldehyde have different safety status in cosmetics vs industrial chemicals?
2,4,6-Trimethyl-3-cyclohexenecarbaldehyde is classified GHS Danger (H315, H317, H319, H334, H400, H412) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check 2,4,6-Trimethyl-3-cyclohexenecarbaldehyde compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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