Poor Cosmetic Ingredient

3-(2-Furyl)Acrylaldehyde

INCI: 3-(2-FURYL)ACRYLALDEHYDE

CAS Number
623-30-3 (mixture of isomers); trans-isomer: 39511-08-5
Function
Primarily a flavoring agent; limited cosmetic use
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes FEMA GRAS 2494 for flavoring at ≤10 ppm. Not specifically regulated as a cosmetic ingredient.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

GHS H314 — Causes severe skin burns and serious eye damage. α,β-unsaturated aldehyde structure is a known structural alert for both skin sensitization (Michael acceptor) and genotoxicity. Solid at room temperature (mp 49–52°C). Strongly recommend against use in leave-on cosmetics without comprehensive SCCS or RIFM safety evaluation.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is 3-(2-Furyl)Acrylaldehyde safe in cosmetics?

GHS H314 — Causes severe skin burns and serious eye damage. α,β-unsaturated aldehyde structure is a known structural alert for both skin sensitization (Michael acceptor) and genotoxicity. Solid at room temperature (mp 49–52°C). Strongly recommend against use in leave-on cosmetics without comprehensive SCCS or RIFM safety evaluation. The EU classifies 3-(2-Furyl)Acrylaldehyde as "permitted". Safety rating: POOR.

Is 3-(2-Furyl)Acrylaldehyde allowed in the EU?

3-(2-Furyl)Acrylaldehyde EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 3-(2-Furyl)Acrylaldehyde do in cosmetics?

3-(2-Furyl)Acrylaldehyde functions as: Primarily a flavoring agent; limited cosmetic use. It is classified as a cosmetic ingredient in our database. CAS number: 623-30-3 (mixture of isomers); trans-isomer: 39511-08-5.

What is the Margin of Safety for 3-(2-Furyl)Acrylaldehyde?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check 3-(2-Furyl)Acrylaldehyde compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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