1,2,4-Benzenetriacetate

INCI: 1,2,4-BENZENETRIACETATE

CAS Number
613-03-6
Function
Hair dye precursor (triacetyl ester of 1,2,4-Trihydroxybenzene)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No separate CIR assessment; functionally linked to 1,2,4-Trihydroxybenzene. Coal tar hair dye exemption may apply with required caution labeling

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Genotoxicity of parent compound; generates ROS and semiquinones upon hydrolysis and auto-oxidation; EU prohibition of parent effectively restricts this ester

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Concern Level: High

Regulatory Flags

eu_banned_cosmetics eu_cosing_listed

Frequently Asked Questions

Is 1,2,4-Benzenetriacetate safe in cosmetics?

Genotoxicity of parent compound; generates ROS and semiquinones upon hydrolysis and auto-oxidation; EU prohibition of parent effectively restricts this ester The EU classifies 1,2,4-Benzenetriacetate as "prohibited". Safety rating: POOR.

Is 1,2,4-Benzenetriacetate allowed in the EU?

1,2,4-Benzenetriacetate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 1,2,4-Benzenetriacetate do in cosmetics?

1,2,4-Benzenetriacetate functions as: Hair dye precursor (triacetyl ester of 1,2,4-Trihydroxybenzene). It is classified as a cosmetic ingredient in our database. CAS number: 613-03-6.

What is the Margin of Safety for 1,2,4-Benzenetriacetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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