Also known as: 3-Cyclohexene-1-carboxaldehyde, dimethyl-, Dimethyl-3-cyclohexene-1-carboxaldehyde, Dimethylcyclohex-3-ene-1-carbaldehyde, Dimethylcyclohex-3-en-1-carbaldehyd, dimetilciclohex-3-eno-1-carbaldehido (+6 more)
INCI: 3,5-DIMETHYL-3-CYCLOHEXENE-1-CARBALDEHYDE
3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde (CAS 27939-60-2) is a cosmetic cosmetic ingredient functioning as Fragrance (Perfuming). Reported NOAEL =150 mg/kg bw/day in Rat (ECHA); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
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Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde.
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Toxicological Studies
2 study endpoints found for 3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
Endpoint
Value
Route
Species
Study Type
Source
NOAEL
=150 mg/kg bw/day
oral
Rat
reproduction developmental
ECHA
NOAEL
=500 mg/kg bw/day
oral
Rat
short-term
ECHA
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification:Restricted (Annex XVII)
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
1900
Source: WHO/JECFA
JECFA Evaluation
(2,4)-, (3,5)- and (3,6)-DIMETHYL-3-CYCLOHEXENYLCARBALDEHYDE | 2010 | No safety concern at current levels of intake when used as a flavouring agent | TRS 960-JECFA 73 | FAS 64-JECFA 73
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrientFragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency ListFDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for 3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde.
Is 3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde safe in cosmetics?
3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.
Is 3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde allowed in the EU?
3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde do in cosmetics?
3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde functions as: Fragrance (Perfuming). It is classified as a cosmetic ingredient in our database. CAS number: 27939-60-2.
What is the NOAEL for 3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde?
The NOAEL (No Observed Adverse Effect Level) for 3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde is =150 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. A total of 2 study endpoints are available. Source: ECHA.
Is 3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde used outside cosmetics?
3,5-Dimethyl-3-Cyclohexene-1-Carbaldehyde also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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