Is 4-Amino-2-Nitrodiphenylamine-2'-Carboxylic Acid safe in cosmetics?
4-Amino-2-Nitrodiphenylamine-2'-Carboxylic Acid has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
4-Amino-2-Nitrodiphenylamine-2'-Carboxylic Acid
Also known as: 2,6-Bis(2-hydroxyethoxy)-3,5-pyridinediamine
INCI: 4-AMINO-2-NITRODIPHENYLAMINE-2'-CARBOXYLIC ACID
4-Amino-2-Nitrodiphenylamine-2'-Carboxylic Acid (CAS 117907-42-3) is a cosmetic cosmetic ingredient functioning as Hair Dyeing (non-oxidative / semi-permanent hair dye). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 117907-42-3 →
Auto-generated CPSR Part A draft with source citations
Function
Hair Dyeing (non-oxidative / semi-permanent hair dye)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-[[3,5-diamino-6-(2-hydroxyethoxy)-2-pyridinyl]oxy]ethanol
InChIKey
FJLWSRYKQCJGGK-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Permitted under coal tar hair dye exemption
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 4-Amino-2-Nitrodiphenylamine-2'-Carboxylic Acid.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1215
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for 4-Amino-2-Nitrodiphenylamine-2'-Carboxylic Acid.
Regulatory Flags
eu_banned_cosmetics
eu_cosing_listed
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to 4-Amino-2-Nitrodiphenylamine-2'-Carboxylic Acid by CAS number or substance name.
Studies
8
Lowest NOAEL
60 mg/kg bw/day
Highest NOAEL
150 mg/kg bw/day
SCCS_vision_codex
Known Synonyms
2,6-Bis(2-hydroxyethoxy)-3,5-pyridinediamine
Regulatory Lists
banned; Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 4-Amino-2-Nitrodiphenylamine-2'-Carboxylic Acid allowed in the EU?
4-Amino-2-Nitrodiphenylamine-2'-Carboxylic Acid EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 4-Amino-2-Nitrodiphenylamine-2'-Carboxylic Acid do in cosmetics?
4-Amino-2-Nitrodiphenylamine-2'-Carboxylic Acid functions as: Hair Dyeing (non-oxidative / semi-permanent hair dye). It is classified as a cosmetic ingredient in our database. CAS number: 117907-42-3.
Compliance Tools
Check 4-Amino-2-Nitrodiphenylamine-2'-Carboxylic Acid compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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