4-Hydroxypropylamino-3-Nitrophenol
INCI: 4-HYDROXYPROPYLAMINO-3-NITROPHENOL
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for 4-Hydroxypropylamino-3-Nitrophenol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 10 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Nitro-aromatic compound prohibited in EU; must comply with purity criteria and display mandatory hair dye warnings on label in permitted jurisdictions.
Regulatory Flags
Frequently Asked Questions
Is 4-Hydroxypropylamino-3-Nitrophenol safe in cosmetics?
Nitro-aromatic compound prohibited in EU; must comply with purity criteria and display mandatory hair dye warnings on label in permitted jurisdictions. The EU classifies 4-Hydroxypropylamino-3-Nitrophenol as "prohibited". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is 4-Hydroxypropylamino-3-Nitrophenol allowed in the EU?
4-Hydroxypropylamino-3-Nitrophenol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 4-Hydroxypropylamino-3-Nitrophenol do in cosmetics?
4-Hydroxypropylamino-3-Nitrophenol functions as: Hair dyeing (oxidative and semi-permanent). It is classified as a cosmetic ingredient in our database. CAS number: 92952-81-3.
What is the Margin of Safety for 4-Hydroxypropylamino-3-Nitrophenol?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 4-Hydroxypropylamino-3-Nitrophenol?
The NOAEL (No Observed Adverse Effect Level) for 4-Hydroxypropylamino-3-Nitrophenol is 10 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
Check 4-Hydroxypropylamino-3-Nitrophenol compliance across multiple jurisdictions:
Related Ingredients
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