4-Terpineol (Terpinen-4-ol)

INCI: TERPINEN-4-OL

CAS Number
562-74-3
Function
Fragrance, denaturant, antimicrobial agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; no specific FDA restriction. CIR assessed as part of Melaleuca alternifolia ingredients

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Oxidized forms are stronger sensitizers; SCCS reproductive toxicity concern for tea tree oil as a whole

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is 4-Terpineol (Terpinen-4-ol) safe in cosmetics?

Oxidized forms are stronger sensitizers; SCCS reproductive toxicity concern for tea tree oil as a whole The EU classifies 4-Terpineol (Terpinen-4-ol) as "permitted". Safety rating: GOOD.

Is 4-Terpineol (Terpinen-4-ol) allowed in the EU?

4-Terpineol (Terpinen-4-ol) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 4-Terpineol (Terpinen-4-ol) do in cosmetics?

4-Terpineol (Terpinen-4-ol) functions as: Fragrance, denaturant, antimicrobial agent. It is classified as a cosmetic ingredient in our database. CAS number: 562-74-3.

What is the Margin of Safety for 4-Terpineol (Terpinen-4-ol)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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