Moderate Cosmetic Ingredient NOAEL Data

4-T-Butyl Benzaldehyde

Also known as: Benzaldehyde, 4-(1,1-dimethylethyl)-, p-t-Butylbenzaldehyde, EINECS 213-367-9, p-tert-Butylbenzaldehyde, UNII-QXF0QY8503

INCI: 4-T-BUTYL BENZALDEHYDE

4-T-Butyl Benzaldehyde (CAS 939-97-9) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient. Reported NOAEL =12.5 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 939-97-9 →

Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient
Safety Rating
MODERATE

Chemistry & Identifiers

EC Number
213-367-9

Regulatory Status

EU EU Status prohibited
US US Status permitted
US Notes Permitted; no specific FDA restriction

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for 4-T-Butyl Benzaldehyde.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for 4-T-Butyl Benzaldehyde. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =12.5 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Deodorizer

Expert Verdict

Expert safety assessment and concern-level summary for 4-T-Butyl Benzaldehyde.

Regulatory Flags

potential-allergen fragrance-component

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to 4-T-Butyl Benzaldehyde by CAS number or substance name.

Studies
1
Lowest NOAEL
12.5 mg/kg bw/day
Highest NOAEL
12.5 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

Benzaldehyde, 4-(1,1-dimethylethyl)- p-t-Butylbenzaldehyde EINECS 213-367-9 p-tert-Butylbenzaldehyde UNII-QXF0QY8503

Chemical Function

Deodorizer

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

ChEMBL ID
CHEMBL242962
View full pharmaceutical profile →

Frequently Asked Questions

Is 4-T-Butyl Benzaldehyde safe in cosmetics?

4-T-Butyl Benzaldehyde has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is 4-T-Butyl Benzaldehyde allowed in the EU?

4-T-Butyl Benzaldehyde EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 4-T-Butyl Benzaldehyde do in cosmetics?

4-T-Butyl Benzaldehyde functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 939-97-9.

What is the NOAEL for 4-T-Butyl Benzaldehyde?

The NOAEL (No Observed Adverse Effect Level) for 4-T-Butyl Benzaldehyde is =12.5 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is 4-T-Butyl Benzaldehyde used outside cosmetics?

4-T-Butyl Benzaldehyde also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does 4-T-Butyl Benzaldehyde have different safety status in cosmetics vs industrial chemicals?

4-T-Butyl Benzaldehyde is prohibited in EU cosmetics but has active industrial GHS classifications (H301, H302, H317, H334, H361, H400, H410).

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