Is 5-Isopropyltropolone safe in cosmetics?
5-Isopropyltropolone has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
5-Isopropyltropolone
INCI: 5-ISOPROPYLTROPOLONE
5-Isopropyltropolone (CAS 618-78-0 (γ-thujaplicin; distinct from hinokitiol/β-thujaplicin, CAS 499-44-5, which is 4-isopropyltropolone)) is a cosmetic cosmetic ingredient functioning as Antimicrobial / Skin Conditioning — tropolone derivatives exhibit. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
618-78-0 (γ-thujaplicin; distinct from hinokitiol/β-thujaplicin, CAS 499-44-5, which is 4-isopropyltropolone)
View industrial chemical safety profile →
Function
Antimicrobial / Skin Conditioning — tropolone derivatives exhibit broad-spectrum antimicrobial activity
Safety Rating
MODERATE
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Permitted — no specific FDA restriction; not an approved OTC active
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 5-Isopropyltropolone.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for 5-Isopropyltropolone.
Frequently Asked Questions
Is 5-Isopropyltropolone allowed in the EU?
5-Isopropyltropolone EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 5-Isopropyltropolone do in cosmetics?
5-Isopropyltropolone functions as: Antimicrobial / Skin Conditioning — tropolone derivatives exhibit broad-spectrum antimicrobial activity. It is classified as a cosmetic ingredient in our database. CAS number: 618-78-0 (γ-thujaplicin; distinct from hinokitiol/β-thujaplicin, CAS 499-44-5, which is 4-isopropyltropolone).
Compliance Tools
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