Is 5-Methoxy-M-Cresol safe in cosmetics?
5-Methoxy-M-Cresol has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
5-Methoxy-M-Cresol
Also known as: o-Isopropoxyphenol, Phenol, 2-(1-methylethoxy)-, Caswell No. 508A, EINECS 225-379-1, EPA Pesticide Chemical Code 205400 (+1 more)
INCI: 5-METHOXY-M-CRESOL
5-Methoxy-M-Cresol (CAS 4812-20-8) is a cosmetic cosmetic ingredient functioning as Perfuming (contains cresol/hydroxytoluene as aromatic-alcoholic component). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 4812-20-8 →
Auto-generated CPSR Part A draft with source citations
Function
Perfuming (contains cresol/hydroxytoluene as aromatic-alcoholic component)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific FDA restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 5-Methoxy-M-Cresol.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for 5-Methoxy-M-Cresol.
Regulatory Flags
fragrance-component
Known Synonyms
o-Isopropoxyphenol
Phenol, 2-(1-methylethoxy)-
Caswell No. 508A
EINECS 225-379-1
EPA Pesticide Chemical Code 205400
2-(1-methylethoxy)phenol
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3182286
Frequently Asked Questions
Is 5-Methoxy-M-Cresol allowed in the EU?
5-Methoxy-M-Cresol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 5-Methoxy-M-Cresol do in cosmetics?
5-Methoxy-M-Cresol functions as: Perfuming (contains cresol/hydroxytoluene as aromatic-alcoholic component). It is classified as a cosmetic ingredient in our database. CAS number: 4812-20-8.
Is 5-Methoxy-M-Cresol used outside cosmetics?
5-Methoxy-M-Cresol also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 5-Methoxy-M-Cresol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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