5-Methoxy-M-Cresol

INCI: 5-METHOXY-M-CRESOL

CAS Number
4812-20-8
Function
Perfuming (contains cresol/hydroxytoluene as aromatic-alcoholic component)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

High dermal absorption (โ‰ค80% class); cresol derivatives warrant careful concentration control; not genotoxic per ECHA REACH data

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Concern Level: Moderate

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is 5-Methoxy-M-Cresol safe in cosmetics?

High dermal absorption (โ‰ค80% class); cresol derivatives warrant careful concentration control; not genotoxic per ECHA REACH data The EU classifies 5-Methoxy-M-Cresol as "permitted". Safety rating: MODERATE.

Is 5-Methoxy-M-Cresol allowed in the EU?

5-Methoxy-M-Cresol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 5-Methoxy-M-Cresol do in cosmetics?

5-Methoxy-M-Cresol functions as: Perfuming (contains cresol/hydroxytoluene as aromatic-alcoholic component). It is classified as a cosmetic ingredient in our database. CAS number: 4812-20-8.

What is the Margin of Safety for 5-Methoxy-M-Cresol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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