7-Hydroxy-3,7-Dimethyl-Octanal/Indole

INCI: 7-HYDROXY-3,7-DIMETHYL-OCTANAL/INDOLE

CAS Number
EC Number 272-683-5 (reaction product; no single CAS — mixture classification)
Function
Perfuming (hydroxycitronellal/indole condensation product; floral-jasmine note)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes No specific FDA restriction; IFRA standards apply

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

H317 skin sensitization classification and H319 serious eye irritation flagged in 20.7% of ECHA notifications; moderate safety profile with concentration restrictions likely applicable.

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is 7-Hydroxy-3,7-Dimethyl-Octanal/Indole safe in cosmetics?

H317 skin sensitization classification and H319 serious eye irritation flagged in 20.7% of ECHA notifications; moderate safety profile with concentration restrictions likely applicable. The EU classifies 7-Hydroxy-3,7-Dimethyl-Octanal/Indole as "restricted". Safety rating: MODERATE.

Is 7-Hydroxy-3,7-Dimethyl-Octanal/Indole allowed in the EU?

7-Hydroxy-3,7-Dimethyl-Octanal/Indole EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does 7-Hydroxy-3,7-Dimethyl-Octanal/Indole do in cosmetics?

7-Hydroxy-3,7-Dimethyl-Octanal/Indole functions as: Perfuming (hydroxycitronellal/indole condensation product; floral-jasmine note). It is classified as a cosmetic ingredient in our database. CAS number: EC Number 272-683-5 (reaction product; no single CAS — mixture classification).

What is the Margin of Safety for 7-Hydroxy-3,7-Dimethyl-Octanal/Indole?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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