8-Cyclohexadecenone

INCI: 8-CYCLOHEXADECENONE

CAS Number
3100-36-5 (also 88642-03-9 for cis/trans mixture)
Function
Perfuming (musk, clean, powdery)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted by FDA; IFRA Transparency List

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Macrocyclic musks are considered environmentally preferable to polycyclic musks with no significant toxicological concerns identified.

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Concern Level: Low

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is 8-Cyclohexadecenone safe in cosmetics?

Macrocyclic musks are considered environmentally preferable to polycyclic musks with no significant toxicological concerns identified. The EU classifies 8-Cyclohexadecenone as "prohibited". Safety rating: GOOD.

Is 8-Cyclohexadecenone allowed in the EU?

8-Cyclohexadecenone EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 8-Cyclohexadecenone do in cosmetics?

8-Cyclohexadecenone functions as: Perfuming (musk, clean, powdery). It is classified as a cosmetic ingredient in our database. CAS number: 3100-36-5 (also 88642-03-9 for cis/trans mixture).

What is the Margin of Safety for 8-Cyclohexadecenone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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