Acetamidoethoxybutyl Trimonium Chloride

INCI: ACETAMIDOETHOXYBUTYL TRIMONIUM CHLORIDE

CAS Number
221375-78-6
Function
Antistatic, hair conditioning, skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR group-assessed with trimoniums โ€” safe in rinse-off products and โ‰ค0.25% in leave-on products

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR concentration cap of 0.25% for leave-on products; ocular irritation possible at higher concentrations

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Concern Level: Low

Frequently Asked Questions

Is Acetamidoethoxybutyl Trimonium Chloride safe in cosmetics?

CIR concentration cap of 0.25% for leave-on products; ocular irritation possible at higher concentrations The EU classifies Acetamidoethoxybutyl Trimonium Chloride as "permitted". Safety rating: GOOD.

Is Acetamidoethoxybutyl Trimonium Chloride allowed in the EU?

Acetamidoethoxybutyl Trimonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acetamidoethoxybutyl Trimonium Chloride do in cosmetics?

Acetamidoethoxybutyl Trimonium Chloride functions as: Antistatic, hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 221375-78-6.

What is the Margin of Safety for Acetamidoethoxybutyl Trimonium Chloride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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