Acetyl Octapeptide-17 Amide

INCI: ACETYL OCTAPEPTIDE-17 AMIDE

CAS Number
Not publicly listed in standard databases
Function
Skin conditioning — EGF-mimicking peptide (Ac-Met-Leu-Lys-Glu-Trp-Glu-Leu-Arg-NH₂)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EGF receptor agonist that promotes cell proliferation. Theoretical concern with growth-factor-mimicking peptides on compromised or pre-cancerous skin; however, use levels are extremely low.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Acetyl Octapeptide-17 Amide safe in cosmetics?

EGF receptor agonist that promotes cell proliferation. Theoretical concern with growth-factor-mimicking peptides on compromised or pre-cancerous skin; however, use levels are extremely low. The EU classifies Acetyl Octapeptide-17 Amide as "permitted". Safety rating: GOOD.

Is Acetyl Octapeptide-17 Amide allowed in the EU?

Acetyl Octapeptide-17 Amide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acetyl Octapeptide-17 Amide do in cosmetics?

Acetyl Octapeptide-17 Amide functions as: Skin conditioning — EGF-mimicking peptide (Ac-Met-Leu-Lys-Glu-Trp-Glu-Leu-Arg-NH₂). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed in standard databases.

What is the Margin of Safety for Acetyl Octapeptide-17 Amide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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