Acetyl Trifluoromethylphenyl Valylglycine

INCI: ACETYL TRIFLUOROMETHYLPHENYL VALYLGLYCINE

CAS Number
379685-96-8 (L-form: 947159-33-3)
Function
Skin Conditioning (anti-aging - enhances skin elasticity, firmness; prevents collagen degradation)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted; permitted under general cosmetic provisions. Patented cosmetic active (US10449133B1).

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

โš  Fluorinated compound - contains CFโ‚ƒ group; long-term environmental/bioaccumulation data not available. Patent describes use at up to 25% which is unusually high for an active. Verify supplier safety dossier and stability of the C-F bonds under formulation conditions.

โš ๏ธ
Concern Level: Low

Frequently Asked Questions

Is Acetyl Trifluoromethylphenyl Valylglycine safe in cosmetics?

โš  Fluorinated compound - contains CFโ‚ƒ group; long-term environmental/bioaccumulation data not available. Patent describes use at up to 25% which is unusually high for an active. Verify supplier safety dossier and stability of the C-F bonds under formulation conditions. The EU classifies Acetyl Trifluoromethylphenyl Valylglycine as "permitted". Safety rating: GOOD.

Is Acetyl Trifluoromethylphenyl Valylglycine allowed in the EU?

Acetyl Trifluoromethylphenyl Valylglycine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acetyl Trifluoromethylphenyl Valylglycine do in cosmetics?

Acetyl Trifluoromethylphenyl Valylglycine functions as: Skin Conditioning (anti-aging - enhances skin elasticity, firmness; prevents collagen degradation). It is classified as a cosmetic ingredient in our database. CAS number: 379685-96-8 (L-form: 947159-33-3).

What is the Margin of Safety for Acetyl Trifluoromethylphenyl Valylglycine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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