Acetyl Tripeptide-30 Citrulline

INCI: ACETYL TRIPEPTIDE-30 CITRULLINE

CAS Number
40968-45-4
Function
Skin Conditioning (anti-aging peptide; MMP inhibitor that prevents ECM degradation; firming/lifting)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted; permitted for cosmetic use under general FDA cosmetic regulations. No CIR monograph specific to this peptide

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

MW below 500 Da means actual dermal penetration is likely; limited published peer-reviewed toxicological data; relies primarily on supplier safety dossiers

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Concern Level: Moderate

Frequently Asked Questions

Is Acetyl Tripeptide-30 Citrulline safe in cosmetics?

MW below 500 Da means actual dermal penetration is likely; limited published peer-reviewed toxicological data; relies primarily on supplier safety dossiers The EU classifies Acetyl Tripeptide-30 Citrulline as "restricted". Safety rating: GOOD.

Is Acetyl Tripeptide-30 Citrulline allowed in the EU?

Acetyl Tripeptide-30 Citrulline EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acetyl Tripeptide-30 Citrulline do in cosmetics?

Acetyl Tripeptide-30 Citrulline functions as: Skin Conditioning (anti-aging peptide; MMP inhibitor that prevents ECM degradation; firming/lifting). It is classified as a cosmetic ingredient in our database. CAS number: 40968-45-4.

What is the Margin of Safety for Acetyl Tripeptide-30 Citrulline?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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