Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
5 study endpoints found for Acid Red 27 (Amaranth). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 47 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 0.1 other | dermal | code:3543 | dermal | REACH |
| NOAEL | 1260 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 50 mg/kg bw/day | oral | mouse | oral | REACH |
| NOAEL | 2462 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Banned in the US; EFSA found not genotoxic or carcinogenic but lowered ADI significantly due to reproductive toxicity at high doses; high-exposure consumers could exceed ADI
Regulatory Flags
Frequently Asked Questions
Is Acid Red 27 (Amaranth) safe in cosmetics?
Banned in the US; EFSA found not genotoxic or carcinogenic but lowered ADI significantly due to reproductive toxicity at high doses; high-exposure consumers could exceed ADI The EU classifies Acid Red 27 (Amaranth) as "permitted". Safety rating: MODERATE. 5 toxicological study endpoint(s) are available in our database.
Is Acid Red 27 (Amaranth) allowed in the EU?
Acid Red 27 (Amaranth) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acid Red 27 (Amaranth) do in cosmetics?
Acid Red 27 (Amaranth) functions as: Cosmetic colorant. It is classified as a cosmetic ingredient in our database. CAS number: 915-67-3.
What is the Margin of Safety for Acid Red 27 (Amaranth)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Acid Red 27 (Amaranth)?
The NOAEL (No Observed Adverse Effect Level) for Acid Red 27 (Amaranth) is 47 mg/kg bw/day based on a oral study via oral route in rat. A total of 5 study endpoints are available. Source: REACH.
Compliance Tools
Check Acid Red 27 (Amaranth) compliance across multiple jurisdictions:
Related Ingredients
Is Acid Red 27 (Amaranth) in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Acid Red 27 (Amaranth) in your formulation.