Moderate Cosmetic Ingredient NOAEL Data

Acid Yellow 1

INCI: CI 10316

CAS Number
846-70-8
Function
Colorant (nitro dye; Naphthol Yellow S)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Ext. D&C Yellow No. 7 โ€” listed for externally applied drugs and cosmetics; certification required

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Acid Yellow 1. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOAEL 30 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

External use only in the US (not for lips, mucous membranes, or ingestion); nitro dye class โ€” verify heavy metal specifications per batch COA

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

colorant eu_cosing_listed

Frequently Asked Questions

Is Acid Yellow 1 safe in cosmetics?

External use only in the US (not for lips, mucous membranes, or ingestion); nitro dye class โ€” verify heavy metal specifications per batch COA The EU classifies Acid Yellow 1 as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Acid Yellow 1 allowed in the EU?

Acid Yellow 1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acid Yellow 1 do in cosmetics?

Acid Yellow 1 functions as: Colorant (nitro dye; Naphthol Yellow S). It is classified as a cosmetic ingredient in our database. CAS number: 846-70-8.

What is the Margin of Safety for Acid Yellow 1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Acid Yellow 1?

The NOAEL (No Observed Adverse Effect Level) for Acid Yellow 1 is 30 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.

๐Ÿ“ฑ

Is Acid Yellow 1 in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Acid Yellow 1 in your formulation.