Moderate Cosmetic Ingredient SCCS/CIR Reviewed

Aldioxa

INCI: ALDIOXA

CAS Number
5579-81-7
Function
Astringent, skin conditioning agent, mild anti-perspirant action, promotes tissue regeneration
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes FDA classified as Category III (insufficient data) for OTC skin protectant drug use; cosmetic use is not prohibited but lacks full FDA safety endorsement

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir
Verdict: unknown

Expert Verdict

CIR designated insufficient data for OTC skin protectant use; cosmetic use permitted but lacks full FDA safety endorsement. Contains aluminum—formulators should consider cumulative aluminum exposure. Notable data gaps: UV absorption, genotoxicity testing, and 28-day dermal toxicity studies.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Aldioxa safe in cosmetics?

CIR designated insufficient data for OTC skin protectant use; cosmetic use permitted but lacks full FDA safety endorsement. Contains aluminum—formulators should consider cumulative aluminum exposure. Notable data gaps: UV absorption, genotoxicity testing, and 28-day dermal toxicity studies. The EU classifies Aldioxa as "permitted". Safety rating: MODERATE. This ingredient has been reviewed by cir.

Is Aldioxa allowed in the EU?

Aldioxa EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aldioxa do in cosmetics?

Aldioxa functions as: Astringent, skin conditioning agent, mild anti-perspirant action, promotes tissue regeneration. It is classified as a cosmetic ingredient in our database. CAS number: 5579-81-7.

What is the Margin of Safety for Aldioxa?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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