Is Aldioxa safe in cosmetics?
Aldioxa has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. This ingredient has been reviewed by CIR Safety Assessment.
Aldioxa
Also known as: Aluminum, dihydroxy(allantoinato)-, EINECS 226-964-4, Chlokale, Peptilate, Aldioxum (+1 more)
INCI: ALDIOXA
Aldioxa (CAS 5579-81-7) is a cosmetic cosmetic ingredient functioning as Astringent, skin conditioning agent, mild anti-perspirant action, promotes. EU Regulation 1223/2009 status: permitted; 1 safety opinion reviewed (CIR Safety Assessment). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
Function
Astringent, skin conditioning agent, mild anti-perspirant action, promotes tissue regeneration
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA classified as Category III (insufficient data) for OTC skin protectant drug use; cosmetic use is not prohibited but lacks full FDA safety endorsement
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Aldioxa.
Calculate MoS for your specific formulation with the MoS Calculator.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
CIR Safety Assessment
Verdict: unknown
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Astringent
Biocide
Editorial summary
Preliminary editorial summary for Aldioxa — not a computed safety verdict. See the sourced toxicological data above.
Known Synonyms
Aluminum, dihydroxy(allantoinato)-
EINECS 226-964-4
Chlokale
Peptilate
Aldioxum
UNII-8T66I31YNK
Chemical Function
Biocide
Astringent
Regulatory Lists
pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
7
Frequently Asked Questions
Is Aldioxa allowed in the EU?
Aldioxa EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Aldioxa do in cosmetics?
Aldioxa functions as: Astringent, skin conditioning agent, mild anti-perspirant action, promotes tissue regeneration. It is classified as a cosmetic ingredient in our database. CAS number: 5579-81-7.
Is Aldioxa used outside cosmetics?
Aldioxa also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Aldioxa compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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