Allantoin PABA

INCI: ALLANTOIN PABA

CAS Number
4207-42-5
Function
Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically reviewed by CIR (the 2010 allantoin report did not include allantoin PABA). PABA itself was an FDA-approved OTC sunscreen active but its use has declined due to adverse reactions.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Allantoin PABA contains PABA, which is linked to allergic dermatitis, photosensitivity, and potential thyroid-disrupting activity; PABA use has declined due to adverse reactions and regulatory restrictions in some regions.

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Concern Level: High

Frequently Asked Questions

Is Allantoin PABA safe in cosmetics?

Allantoin PABA contains PABA, which is linked to allergic dermatitis, photosensitivity, and potential thyroid-disrupting activity; PABA use has declined due to adverse reactions and regulatory restrictions in some regions. The EU classifies Allantoin PABA as "permitted". Safety rating: MODERATE.

Is Allantoin PABA allowed in the EU?

Allantoin PABA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Allantoin PABA do in cosmetics?

Allantoin PABA functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 4207-42-5.

What is the Margin of Safety for Allantoin PABA?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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