Allylanisole

INCI: ALLYLANISOLE

CAS Number
140-67-0 (estragole / methyl chavicol / 4-allylanisole)
Function
Fragrance; denaturant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
EU Max Conc. 0.01%
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Generally permitted in fragrances; FEMA GRAS for food use but cosmetic use is not specifically restricted by FDA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Genotoxic and potentially carcinogenic. SCCS and EFSA have identified estragole as a genotoxic carcinogen via DNA adduct formation. Must not be intentionally added; strict concentration limits apply when naturally present.

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Concern Level: High

Regulatory Flags

fragrance-component natural-origin

Frequently Asked Questions

Is Allylanisole safe in cosmetics?

Genotoxic and potentially carcinogenic. SCCS and EFSA have identified estragole as a genotoxic carcinogen via DNA adduct formation. Must not be intentionally added; strict concentration limits apply when naturally present. The EU classifies Allylanisole as "prohibited". Safety rating: MODERATE.

Is Allylanisole allowed in the EU?

Allylanisole EU regulatory status: prohibited. Maximum allowed concentration: 0.01%. This is based on EU Regulation 1223/2009 and its amendments.

What does Allylanisole do in cosmetics?

Allylanisole functions as: Fragrance; denaturant. It is classified as a cosmetic ingredient in our database. CAS number: 140-67-0 (estragole / methyl chavicol / 4-allylanisole).

What is the Margin of Safety for Allylanisole?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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