Moderate Cosmetic Ingredient

Aloe Arborescens Leaf Protoplasts

INCI: ALOE ARBORESCENS LEAF PROTOPLASTS

CAS Number
Not individually assigned
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted; CIR 2007 included this ingredient but did not specifically require 28-day dermal tox for it (protoplasts were listed but not called out for additional studies)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Unique preparation method - protoplasts release intracellular components that differ from standard extracts; anthraquinone ≤50 ppm mandatory; virtually no published use-concentration data

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Concern Level: Moderate

Frequently Asked Questions

Is Aloe Arborescens Leaf Protoplasts safe in cosmetics?

Unique preparation method - protoplasts release intracellular components that differ from standard extracts; anthraquinone ≤50 ppm mandatory; virtually no published use-concentration data The EU classifies Aloe Arborescens Leaf Protoplasts as "permitted". Safety rating: MODERATE.

Is Aloe Arborescens Leaf Protoplasts allowed in the EU?

Aloe Arborescens Leaf Protoplasts EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aloe Arborescens Leaf Protoplasts do in cosmetics?

Aloe Arborescens Leaf Protoplasts functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned.

What is the Margin of Safety for Aloe Arborescens Leaf Protoplasts?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Aloe Arborescens Leaf Protoplasts compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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