Moderate Cosmetic Ingredient NOAEL Data GHS Classified

Aluminum Chloride

INCI: ALUMINUM CHLORIDE

CAS Number
7446-70-0
Function
Antiperspirant, Astringent, Deodorant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 6.18%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted as OTC antiperspirant active under FDA Monograph (21 CFR 350); max 15% anhydrous in aerosol, 25% in other dosage forms

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Aluminum Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 200 mg/kg bw/day oral rat oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion.

Expert Verdict

Strong irritant on broken or shaved skin; SCCS 2024 opinion warns aggregate aluminum exposure may exceed safe limits at highest exposure ranges

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Concern Level: Moderate

Frequently Asked Questions

Is Aluminum Chloride safe in cosmetics?

Strong irritant on broken or shaved skin; SCCS 2024 opinion warns aggregate aluminum exposure may exceed safe limits at highest exposure ranges The EU classifies Aluminum Chloride as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Aluminum Chloride allowed in the EU?

Aluminum Chloride EU regulatory status: permitted. Maximum allowed concentration: 6.18%. This is based on EU Regulation 1223/2009 and its amendments.

What does Aluminum Chloride do in cosmetics?

Aluminum Chloride functions as: Antiperspirant, Astringent, Deodorant. It is classified as a cosmetic ingredient in our database. CAS number: 7446-70-0.

What is the Margin of Safety for Aluminum Chloride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Aluminum Chloride?

The NOAEL (No Observed Adverse Effect Level) for Aluminum Chloride is 200 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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