Aluminum Sesquichlorohydrate

INCI: ALUMINUM SESQUICHLOROHYDRATE

CAS Number
11089-92-2
Function
Antiperspirant, Astringent, Deodorant
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status restricted
EU Max Conc. Spray antiperspirant/deodorant: ≤10.60% (as Al); non-spray antiperspirant/deodorant: ≤6.25% (as Al); lipsticks: ≤0.77% (as Al); toothpaste: ≤2.65% (as Al)
🇺🇸 US Status permitted
US Notes Regulated as an OTC antiperspirant active ingredient under FDA Monograph M019 (21 CFR 350); permitted up to 25% in antiperspirant formulations; CIR deferred full safety assessment to FDA given OTC drug classification; not prohibited or restricted for cosmetic-only use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Well-established antiperspirant active with decades of safe use in OTC drug products. FDA regulates as a recognized safe and effective antiperspirant active up to 25%. EU SCCS concluded safe at concentration limits defined by product category (non-spray ≤6.25% Al, spray ≤10.60% Al). Dermal absorption is negligibly low (<0.01%) based on robust 26Al tracer human studies — systemic exposure does not meaningfully add to background aluminium burden. No causal link to breast cancer or Alzheimer's disease established in epidemiological literature. Pending EU Annex III formal codification via Omnibus Act 2 (expected Q1 2026). Use within SCCS-recommended concentration windows poses negligible systemic risk.

⚠️
Concern Level: Low

Regulatory Flags

fda-otc-drug-antiperspirant CIR-deferred-to-FDA SCCS-assessed EU-annex-III-pending extremely-low-dermal-absorption non-sensitizing concentration-limits-by-product-type no-cancer-link-established gentler-than-aluminum-chloride omnibus-act-2-pending

Frequently Asked Questions

Is Aluminum Sesquichlorohydrate safe in cosmetics?

Well-established antiperspirant active with decades of safe use in OTC drug products. FDA regulates as a recognized safe and effective antiperspirant active up to 25%. EU SCCS concluded safe at concentration limits defined by product category (non-spray ≤6.25% Al, spray ≤10.60% Al). Dermal absorption is negligibly low (<0.01%) based on robust 26Al tracer human studies — systemic exposure does not meaningfully add to background aluminium burden. No causal link to breast cancer or Alzheimer's disease established in epidemiological literature. Pending EU Annex III formal codification via Omnibus Act 2 (expected Q1 2026). Use within SCCS-recommended concentration windows poses negligible systemic risk. The EU classifies Aluminum Sesquichlorohydrate as "restricted". Safety rating: GOOD.

Is Aluminum Sesquichlorohydrate allowed in the EU?

Aluminum Sesquichlorohydrate EU regulatory status: restricted. Maximum allowed concentration: Spray antiperspirant/deodorant: ≤10.60% (as Al); non-spray antiperspirant/deodorant: ≤6.25% (as Al); lipsticks: ≤0.77% (as Al); toothpaste: ≤2.65% (as Al). This is based on EU Regulation 1223/2009 and its amendments.

What does Aluminum Sesquichlorohydrate do in cosmetics?

Aluminum Sesquichlorohydrate functions as: Antiperspirant, Astringent, Deodorant. It is classified as a cosmetic ingredient in our database. CAS number: 11089-92-2.

What is the Margin of Safety for Aluminum Sesquichlorohydrate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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