Excellent Cosmetic Ingredient NOAEL Data GHS Classified SCCS/CIR Reviewed

Barium Sulfate Synth

INCI: BARIUM SULFATE

CAS Number
7727-43-7
Function
colorant, opacifying
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted colorant in cosmetics; CIR-assessed safe up to 37% in leave-on and 0.99% in rinse-off products when formulated non-irritating.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Barium Sulfate Synth. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 2000 ppm oral - oral REACH
NOAEL 2000 ppm oral rat oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Long-term Exposure Effects
Repeated or prolonged inhalation of dust particles may cause effects on the lungs. This may result in baritosis (a form of benign pneumoconiosis).
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol.

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir
Verdict: safe

lfate should be formulated to be non- irritating. The Panel concluded that barium sulfate is safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating. Keywords barium sulfate, safety, cosmetics Introduction The saf

Expert Verdict

Insoluble inorganic mineral approved as a cosmetic colorant and opacifier in both EU and US; CIR-confirmed safe with extensive medical use precedent; no penetration or sensitization concerns.

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Concern Level: None

Regulatory Flags

eu_cosing_listed

Frequently Asked Questions

Is Barium Sulfate Synth safe in cosmetics?

Insoluble inorganic mineral approved as a cosmetic colorant and opacifier in both EU and US; CIR-confirmed safe with extensive medical use precedent; no penetration or sensitization concerns. The EU classifies Barium Sulfate Synth as "permitted". Safety rating: EXCELLENT. 2 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.

Is Barium Sulfate Synth allowed in the EU?

Barium Sulfate Synth EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Barium Sulfate Synth do in cosmetics?

Barium Sulfate Synth functions as: colorant, opacifying. It is classified as a cosmetic ingredient in our database. CAS number: 7727-43-7.

What is the Margin of Safety for Barium Sulfate Synth?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Barium Sulfate Synth?

The NOAEL (No Observed Adverse Effect Level) for Barium Sulfate Synth is 2000 ppm based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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