Amidinoglycine

INCI: AMIDINOGLYCINE

CAS Number
352-97-6 (guanidinoacetic acid — structural match for "amidino" + glycine)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted by FDA; no CIR monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No published cosmetic-specific safety assessment; not recommended for fragrance use; very limited use in commercial formulations.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Amidinoglycine safe in cosmetics?

No published cosmetic-specific safety assessment; not recommended for fragrance use; very limited use in commercial formulations. The EU classifies Amidinoglycine as "permitted". Safety rating: MODERATE.

Is Amidinoglycine allowed in the EU?

Amidinoglycine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Amidinoglycine do in cosmetics?

Amidinoglycine functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 352-97-6 (guanidinoacetic acid — structural match for "amidino" + glycine).

What is the Margin of Safety for Amidinoglycine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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