Amylcyclopentenone

INCI: AMYLCYCLOPENTENONE

CAS Number
25564-22-1 (2-pentyl-2-cyclopenten-1-one)
Function
Fragrance (jasmine bases, floral compositions)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted by FDA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

The α,β-unsaturated cyclopentenone motif is a recognized structural alert for skin sensitization (Michael acceptor reactivity with nucleophilic amino acids on skin proteins); formulators should adhere to IFRA concentration limits and monitor for sensitization in repeated use products

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Amylcyclopentenone safe in cosmetics?

The α,β-unsaturated cyclopentenone motif is a recognized structural alert for skin sensitization (Michael acceptor reactivity with nucleophilic amino acids on skin proteins); formulators should adhere to IFRA concentration limits and monitor for sensitization in repeated use products The EU classifies Amylcyclopentenone as "permitted". Safety rating: MODERATE.

Is Amylcyclopentenone allowed in the EU?

Amylcyclopentenone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Amylcyclopentenone do in cosmetics?

Amylcyclopentenone functions as: Fragrance (jasmine bases, floral compositions). It is classified as a cosmetic ingredient in our database. CAS number: 25564-22-1 (2-pentyl-2-cyclopenten-1-one).

What is the Margin of Safety for Amylcyclopentenone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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