Good Cosmetic Ingredient NOAEL Data

Amyloglucosidase

INCI: AMYLOGLUCOSIDASE

CAS Number
9032-08-0
Function
Skin conditioning (enzyme)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA GRAS as food enzyme; not restricted in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Amyloglucosidase. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >=1519.2 mg/kg bw/day oral rat oral REACH

Expert Verdict

Occupational inhalation allergen in industrial enzyme dust handling; not a concern in finished cosmetic products.

โš ๏ธ
Concern Level: Low

Regulatory Flags

potential-allergen eu_children_restricted

Frequently Asked Questions

Is Amyloglucosidase safe in cosmetics?

Occupational inhalation allergen in industrial enzyme dust handling; not a concern in finished cosmetic products. The EU classifies Amyloglucosidase as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Amyloglucosidase allowed in the EU?

Amyloglucosidase EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Amyloglucosidase do in cosmetics?

Amyloglucosidase functions as: Skin conditioning (enzyme). It is classified as a cosmetic ingredient in our database. CAS number: 9032-08-0.

What is the Margin of Safety for Amyloglucosidase?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Amyloglucosidase?

The NOAEL (No Observed Adverse Effect Level) for Amyloglucosidase is >=1519.2 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

๐Ÿ“ฑ

Is Amyloglucosidase in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Amyloglucosidase in your formulation.