Is MUSK R1 safe in cosmetics?
MUSK R1 has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
MUSK R1
Also known as: 11-oxahexadecan-16-olide, Decanoic acid, 10-((5-hydroxypentyl)oxy)-, o-lactone, EINECS 222-225-5, 16-Hydroxy-11-oxahexadecanoic acid, omega-lactone, 11-Oxahexadecanolide
MUSK R1 (CAS 3391-83-1) is a cosmetic cosmetic ingredient functioning as Perfuming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 3391-83-1 →
Auto-generated CPSR Part A draft with source citations
Function
Perfuming
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
1,7-dioxacycloheptadecan-8-one
InChIKey
MKEIDVFLAWJKMY-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 6750 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for MUSK R1.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
ifra_fragrance
Known Synonyms
11-oxahexadecan-16-olide
Decanoic acid, 10-((5-hydroxypentyl)oxy)-, o-lactone
EINECS 222-225-5
16-Hydroxy-11-oxahexadecanoic acid, omega-lactone
11-Oxahexadecanolide
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
consumer_product
Australian Status
AICIS status: listed
Frequently Asked Questions
Is MUSK R1 allowed in the EU?
MUSK R1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does MUSK R1 do in cosmetics?
MUSK R1 functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 3391-83-1.
Is MUSK R1 used outside cosmetics?
MUSK R1 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check MUSK R1 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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