Anhydroxylitol

INCI: ANHYDROXYLITOL

CAS Number
53448-53-6
Function
Skin Conditioning Agent – Humectant
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR Final Report (September 2021): Safe; 153 reported uses in VCRP — the most widely used ingredient in this saccharide group

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Safe for cosmetic use; CIR determined no identified risk substances in composition and myocarditis findings in rat studies were species-specific background findings with no relevance to human risk.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Anhydroxylitol safe in cosmetics?

Safe for cosmetic use; CIR determined no identified risk substances in composition and myocarditis findings in rat studies were species-specific background findings with no relevance to human risk. The EU classifies Anhydroxylitol as "permitted". Safety rating: GOOD.

Is Anhydroxylitol allowed in the EU?

Anhydroxylitol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Anhydroxylitol do in cosmetics?

Anhydroxylitol functions as: Skin Conditioning Agent – Humectant. It is classified as a cosmetic ingredient in our database. CAS number: 53448-53-6.

What is the Margin of Safety for Anhydroxylitol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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