Annona Muricata Fruit

INCI: ANNONA MURICATA FRUIT

CAS Number
93165-81-2
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific restriction; manufacturer responsibility under MoCRA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EFSA-listed botanical of concern; 1-year oral rat study with fruit juice showed tau protein phosphorylation in brain; fruit pulp ACG content varies by cultivar and maturity; topical use at low concentrations likely lower risk than oral, but no dermal NOAEL exists

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Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Annona Muricata Fruit safe in cosmetics?

EFSA-listed botanical of concern; 1-year oral rat study with fruit juice showed tau protein phosphorylation in brain; fruit pulp ACG content varies by cultivar and maturity; topical use at low concentrations likely lower risk than oral, but no dermal NOAEL exists The EU classifies Annona Muricata Fruit as "permitted". Safety rating: MODERATE.

Is Annona Muricata Fruit allowed in the EU?

Annona Muricata Fruit EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Annona Muricata Fruit do in cosmetics?

Annona Muricata Fruit functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 93165-81-2.

What is the Margin of Safety for Annona Muricata Fruit?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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