Good Cosmetic Ingredient NOAEL Data

Ar-Isopropylphenylacetaldehyde

INCI: AR-ISOPROPYLPHENYLACETALDEHYDE

CAS Number
4395-92-0
Function
Fragrance
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; no specific FDA restriction; RIFM safety data available

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Ar-Isopropylphenylacetaldehyde. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 19 mg/kg bw/day oral rat Subchronic COSMOS_DB
dose_tested 19 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

Aromatic aldehyde with haptenation potential; maintain IFRA-compliant concentrations; declare under PARFUM unless otherwise required.

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Ar-Isopropylphenylacetaldehyde safe in cosmetics?

Aromatic aldehyde with haptenation potential; maintain IFRA-compliant concentrations; declare under PARFUM unless otherwise required. The EU classifies Ar-Isopropylphenylacetaldehyde as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Ar-Isopropylphenylacetaldehyde allowed in the EU?

Ar-Isopropylphenylacetaldehyde EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ar-Isopropylphenylacetaldehyde do in cosmetics?

Ar-Isopropylphenylacetaldehyde functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 4395-92-0.

What is the Margin of Safety for Ar-Isopropylphenylacetaldehyde?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Ar-Isopropylphenylacetaldehyde?

The NOAEL (No Observed Adverse Effect Level) for Ar-Isopropylphenylacetaldehyde is 19 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

๐Ÿ“ฑ

Is Ar-Isopropylphenylacetaldehyde in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Ar-Isopropylphenylacetaldehyde in your formulation.