Artemisinin

INCI: ARTEMISININ

CAS Number
63968-64-9
Function
Antimicrobial, Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted by FDA for cosmetics; no color additive listing needed. Known primarily as an antimalarial drug (FDA-approved pharmaceutical); cosmetic use is self-regulated under MoCRA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potent pharmacological activity with antimalarial and cytotoxic properties at higher concentrations; cross-reactivity with other sesquiterpene lactones possible. Use at very low concentrations only.

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Concern Level: High

Frequently Asked Questions

Is Artemisinin safe in cosmetics?

Potent pharmacological activity with antimalarial and cytotoxic properties at higher concentrations; cross-reactivity with other sesquiterpene lactones possible. Use at very low concentrations only. The EU classifies Artemisinin as "permitted". Safety rating: MODERATE.

Is Artemisinin allowed in the EU?

Artemisinin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Artemisinin do in cosmetics?

Artemisinin functions as: Antimicrobial, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 63968-64-9.

What is the Margin of Safety for Artemisinin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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