Azelaoyl Dipeptide-27

INCI: AZELAOYL DIPEPTIDE-27

CAS Number
Not publicly assigned in major registries
Function
Skin conditioning (peptide-class ingredient)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - not prohibited or restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Very limited published safety data; as a synthetic peptide, generally expected to have low toxicity and good skin tolerance. No specific safety flags in CosIng. Synthetic peptide combining azelaic acid with a specific dipeptide chain; designed to leverage both the anti-inflammatory properties of azelaic acid and the signaling activity of the peptide moiety

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Concern Level: High

Frequently Asked Questions

Is Azelaoyl Dipeptide-27 safe in cosmetics?

Very limited published safety data; as a synthetic peptide, generally expected to have low toxicity and good skin tolerance. No specific safety flags in CosIng. Synthetic peptide combining azelaic acid with a specific dipeptide chain; designed to leverage both the anti-inflammatory properties of azelaic acid and the signaling activity of the peptide moiety The EU classifies Azelaoyl Dipeptide-27 as "prohibited". Safety rating: MODERATE.

Is Azelaoyl Dipeptide-27 allowed in the EU?

Azelaoyl Dipeptide-27 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Azelaoyl Dipeptide-27 do in cosmetics?

Azelaoyl Dipeptide-27 functions as: Skin conditioning (peptide-class ingredient). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned in major registries.

What is the Margin of Safety for Azelaoyl Dipeptide-27?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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