Moderate Cosmetic Ingredient

Bacillus/Larrea Mexicana/Soybean Ferment Filtrate

INCI: BACILLUS/LARREA MEXICANA/SOYBEAN FERMENT FILTRATE

CAS Number
Not assigned
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status restricted
US Notes Allowed but warrants caution-Larrea (chaparral/creosote bush) has been flagged by FDA for hepatotoxicity concerns in oral supplements; topical cosmetic use is not specifically restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Elevated concern. Larrea mexicana contains nordihydroguaiaretic acid (NDGA), a potent antioxidant but also a known hepatotoxin orally and potential skin sensitizer; thorough safety assessment recommended. Creosote bush is rich in lignans and NDGA; Bacillus fermentation with soybean as co-substrate may modify the NDGA profile; biotechnology/plant biotechnology origin

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Bacillus/Larrea Mexicana/Soybean Ferment Filtrate safe in cosmetics?

Elevated concern. Larrea mexicana contains nordihydroguaiaretic acid (NDGA), a potent antioxidant but also a known hepatotoxin orally and potential skin sensitizer; thorough safety assessment recommended. Creosote bush is rich in lignans and NDGA; Bacillus fermentation with soybean as co-substrate may modify the NDGA profile; biotechnology/plant biotechnology origin The EU classifies Bacillus/Larrea Mexicana/Soybean Ferment Filtrate as "permitted". Safety rating: MODERATE.

Is Bacillus/Larrea Mexicana/Soybean Ferment Filtrate allowed in the EU?

Bacillus/Larrea Mexicana/Soybean Ferment Filtrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bacillus/Larrea Mexicana/Soybean Ferment Filtrate do in cosmetics?

Bacillus/Larrea Mexicana/Soybean Ferment Filtrate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Bacillus/Larrea Mexicana/Soybean Ferment Filtrate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Bacillus/Larrea Mexicana/Soybean Ferment Filtrate compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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