Berberis Vulgaris Root Extract

INCI: BERBERIS VULGARIS ROOT EXTRACT

CAS Number
84649-92-3 / 8054-40-8
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated; berberine is not FDA-approved as a drug ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Same concerns as Berberis aristata root โ€” high alkaloid content. Specify berberine + palmatine + jatrorrhizine levels on CoA. Monitor EFSA opinion timeline for potential restrictions. Cytotoxicity data recommended at intended use concentration.

โš ๏ธ
Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Berberis Vulgaris Root Extract safe in cosmetics?

Same concerns as Berberis aristata root โ€” high alkaloid content. Specify berberine + palmatine + jatrorrhizine levels on CoA. Monitor EFSA opinion timeline for potential restrictions. Cytotoxicity data recommended at intended use concentration. The EU classifies Berberis Vulgaris Root Extract as "prohibited". Safety rating: MODERATE.

Is Berberis Vulgaris Root Extract allowed in the EU?

Berberis Vulgaris Root Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Berberis Vulgaris Root Extract do in cosmetics?

Berberis Vulgaris Root Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84649-92-3 / 8054-40-8.

What is the Margin of Safety for Berberis Vulgaris Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Berberis Vulgaris Root Extract in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Berberis Vulgaris Root Extract in your formulation.