Regulatory Status
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Safety Data
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Expert Verdict
Contains berberine (uterotonic, cytotoxic at high doses); potential isoquinoline alkaloid contamination depending on extraction solvent; no CIR safety assessment available; CPSR assessor will require supplier Certificate of Analysis with berberine quantification
Regulatory Flags
Frequently Asked Questions
Is Berberis Vulgaris Stem Extract safe in cosmetics?
Contains berberine (uterotonic, cytotoxic at high doses); potential isoquinoline alkaloid contamination depending on extraction solvent; no CIR safety assessment available; CPSR assessor will require supplier Certificate of Analysis with berberine quantification The EU classifies Berberis Vulgaris Stem Extract as "prohibited". Safety rating: MODERATE.
Is Berberis Vulgaris Stem Extract allowed in the EU?
Berberis Vulgaris Stem Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Berberis Vulgaris Stem Extract do in cosmetics?
Berberis Vulgaris Stem Extract functions as: Antimicrobial, skin conditioning (anti-inflammatory, antibacterial via berberine alkaloids). It is classified as a cosmetic ingredient in our database. CAS number: 84649-92-3 (generic *Berberis vulgaris* extract).
What is the Margin of Safety for Berberis Vulgaris Stem Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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