Regulatory Status
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Safety Data
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Expert Verdict
Generally well-tolerated; no significant adverse effects reported in literature. As with all peptides, patch testing is advisable for sensitive individuals. Conjugate of hexapeptide-2 and biotin (vitamin B7); marketed as Biotide2000; clinical studies showed significant fine wrinkle reduction after 9 weeks
Frequently Asked Questions
Is Biotinoyl Hexapeptide-2 Amide safe in cosmetics?
Generally well-tolerated; no significant adverse effects reported in literature. As with all peptides, patch testing is advisable for sensitive individuals. Conjugate of hexapeptide-2 and biotin (vitamin B7); marketed as Biotide2000; clinical studies showed significant fine wrinkle reduction after 9 weeks The EU classifies Biotinoyl Hexapeptide-2 Amide as "prohibited". Safety rating: MODERATE.
Is Biotinoyl Hexapeptide-2 Amide allowed in the EU?
Biotinoyl Hexapeptide-2 Amide EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Biotinoyl Hexapeptide-2 Amide do in cosmetics?
Biotinoyl Hexapeptide-2 Amide functions as: Skin conditioning - specifically stimulates collagen gene expression in fibroblasts and keratinocytes; anti-wrinkle, anti-aging, skin repairing, wound healing. It is classified as a cosmetic ingredient in our database. CAS number: 1894171-15-3.
What is the Margin of Safety for Biotinoyl Hexapeptide-2 Amide?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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