Bis(Tripeptide-1) Copper Acetate

INCI: BIS(TRIPEPTIDE-1) COPPER ACETATE (COSING REF NO. 83545)

CAS Number
130120-57-9
Function
Skin conditioning; promotes collagen synthesis, wound healing, and hair growth stimulation
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no specific prohibition; subject to general safety requirements. EWG hazard score: 1 (low concern)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Generally considered safe at typical use levels. Contains copper ions - excessive concentrations could theoretically cause irritation, but formulation levels are very low (usually ppm range). A copper-complexed dimer of Tripeptide-1 (GHK peptide - Glycyl-L-Histidyl-L-Lysine) with acetate counter-ion. Appears as a clear bluish liquid due to copper ions. Originally isolated from human plasma; stimulates dermal cell proliferation, enhances skin elasticity, reduces fine lines, and strengthens hai...

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Concern Level: Moderate

Frequently Asked Questions

Is Bis(Tripeptide-1) Copper Acetate safe in cosmetics?

Generally considered safe at typical use levels. Contains copper ions - excessive concentrations could theoretically cause irritation, but formulation levels are very low (usually ppm range). A copper-complexed dimer of Tripeptide-1 (GHK peptide - Glycyl-L-Histidyl-L-Lysine) with acetate counter-ion. Appears as a clear bluish liquid due to copper ions. Originally isolated from human plasma; stimulates dermal cell proliferation, enhances skin elasticity, reduces fine lines, and strengthens hai... The EU classifies Bis(Tripeptide-1) Copper Acetate as "permitted". Safety rating: MODERATE.

Is Bis(Tripeptide-1) Copper Acetate allowed in the EU?

Bis(Tripeptide-1) Copper Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bis(Tripeptide-1) Copper Acetate do in cosmetics?

Bis(Tripeptide-1) Copper Acetate functions as: Skin conditioning; promotes collagen synthesis, wound healing, and hair growth stimulation. It is classified as a cosmetic ingredient in our database. CAS number: 130120-57-9.

What is the Margin of Safety for Bis(Tripeptide-1) Copper Acetate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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