Brucea Amarissima Gall Extract

INCI: BRUCEA AMARISSIMA GALL EXTRACT

CAS Number
Not assigned
Function
Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No published MoS โ€” critical data gap given known cytotoxic constituents

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains quassinoids with documented cytotoxicity; Safety Assessor will likely require quantified quassinoid content, in vitro genotoxicity data, and dermal irritation/sensitization data; traditional medicine use does not establish cosmetic safety; robust supplier toxicological dossier mandatory

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Brucea Amarissima Gall Extract safe in cosmetics?

Contains quassinoids with documented cytotoxicity; Safety Assessor will likely require quantified quassinoid content, in vitro genotoxicity data, and dermal irritation/sensitization data; traditional medicine use does not establish cosmetic safety; robust supplier toxicological dossier mandatory The EU classifies Brucea Amarissima Gall Extract as "permitted". Safety rating: MODERATE.

Is Brucea Amarissima Gall Extract allowed in the EU?

Brucea Amarissima Gall Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Brucea Amarissima Gall Extract do in cosmetics?

Brucea Amarissima Gall Extract functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Brucea Amarissima Gall Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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