Is Butylphthalide safe in cosmetics?
Butylphthalide has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
MODERATE
Cosmetic Ingredient
Butylphthalide
INCI: BUTYLPHTHALIDE
Butylphthalide (CAS 6066-49-5 (3-n-Butylphthalide)) is a cosmetic cosmetic ingredient functioning as Fragrance (naturally occurring in celery seed oil). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 6066-49-5 (3-n-Butylphthalide) →
Function
Fragrance (naturally occurring in celery seed oil)
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Insufficient data. No cosmetic-specific margin of safety calculation published.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Butylphthalide.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Butylphthalide — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fragrance-component
Frequently Asked Questions
Is Butylphthalide allowed in the EU?
Butylphthalide EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Butylphthalide do in cosmetics?
Butylphthalide functions as: Fragrance (naturally occurring in celery seed oil). It is classified as a cosmetic ingredient in our database. CAS number: 6066-49-5 (3-n-Butylphthalide).
Compliance Tools
Check Butylphthalide compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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