Butyroyl Pentapeptide-24

INCI: BUTYROYL PENTAPEPTIDE-24

CAS Number
Not assigned (novel synthetic peptide)
Function
Skin Conditioning (anti-aging signal peptide; stimulates collagen synthesis)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not established โ€” no published NOAEL/systemic exposure data to calculate MoS

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Novel synthetic peptide with no CIR review and no published margin of safety. Lipidated structure may enhance absorption compared to free peptide. Supplier safety dossier required for cosmetic product safety report.

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Concern Level: Moderate

Frequently Asked Questions

Is Butyroyl Pentapeptide-24 safe in cosmetics?

Novel synthetic peptide with no CIR review and no published margin of safety. Lipidated structure may enhance absorption compared to free peptide. Supplier safety dossier required for cosmetic product safety report. The EU classifies Butyroyl Pentapeptide-24 as "permitted". Safety rating: MODERATE.

Is Butyroyl Pentapeptide-24 allowed in the EU?

Butyroyl Pentapeptide-24 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Butyroyl Pentapeptide-24 do in cosmetics?

Butyroyl Pentapeptide-24 functions as: Skin Conditioning (anti-aging signal peptide; stimulates collagen synthesis). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (novel synthetic peptide).

What is the Margin of Safety for Butyroyl Pentapeptide-24?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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