Is Butyroyl Trihexyl Citrate safe in cosmetics?
Butyroyl Trihexyl Citrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Butyroyl Trihexyl Citrate
Also known as: N-BUTYRYL TRI-N-HEXYL CITRATE, 1,2,3-Propanetricarboxylic acid, 2-(1-oxobutoxy)-, 1,2,3-trihexyl ester, 1,2,3-Propanetricarboxylic acid, 2-(1-oxobutoxy)-, trihexyl ester, Butyryl trihexyl citrate
INCI: BUTYROYL TRIHEXYL CITRATE
Butyroyl Trihexyl Citrate (CAS 82469-79-2) is a cosmetic cosmetic ingredient functioning as Plasticizer; skin conditioning agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 82469-79-2 →
Auto-generated CPSR Part A draft with source citations
Function
Plasticizer; skin conditioning agent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
trihexyl 2-butanoyloxypropane-1,2,3-tricarboxylate
InChIKey
GWVUTNGDMGTPFE-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Likely adequate — related citrate esters (e.g., triethylhexyl citrate) have MoS >100 in published assessments
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Butyroyl Trihexyl Citrate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Plasticizer
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Butyroyl Trihexyl Citrate.
Known Synonyms
N-BUTYRYL TRI-N-HEXYL CITRATE
1,2,3-Propanetricarboxylic acid, 2-(1-oxobutoxy)-, 1,2,3-trihexyl ester
1,2,3-Propanetricarboxylic acid, 2-(1-oxobutoxy)-, trihexyl ester
Butyryl trihexyl citrate
Chemical Function
Softener and conditioner
Plasticizer
Regulatory Lists
Europe; plastic_additive
Australian Status
AICIS status: listed_with_terms
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3185537
Frequently Asked Questions
Is Butyroyl Trihexyl Citrate allowed in the EU?
Butyroyl Trihexyl Citrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Butyroyl Trihexyl Citrate do in cosmetics?
Butyroyl Trihexyl Citrate functions as: Plasticizer; skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 82469-79-2.
Is Butyroyl Trihexyl Citrate used outside cosmetics?
Butyroyl Trihexyl Citrate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Butyroyl Trihexyl Citrate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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