Good Cosmetic Ingredient NOAEL Data

C13-15 Alkane

Also known as: Hydrotreated middle distillate (petroleum), Distillates (petroleum), straight run middle, hydrotreated, Amoco NT-45 process oil, EINECS 265-148-2, UNII-114P5I43UJ

INCI: C13-15 ALKANE

C13-15 Alkane (CAS 64742-46-7) is a cosmetic cosmetic ingredient functioning as Emollient, Solvent. Reported NOAEL =750 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 64742-46-7 →

Auto-generated CPSR Part A draft with source citations
Function
Emollient, Solvent
Safety Rating
GOOD

Chemistry & Identifiers

EC Number
265-148-2

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Not a sunscreen active; no specific FDA restrictions.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for C13-15 Alkane.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for C13-15 Alkane. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =750 mg/kg bw/day oral Rat subchronic ToxValDB_ECHA_IUCLID

EU CLP Annex VI Harmonized Classification

Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.

Signal Word
Danger
Pictograms
Health Hazard
Hazard Class and Category
Carc. 1B
Hazard Statements
  • H350 May cause cancer

Inserted via ATP: ATP02

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10,000,000 - 100,000,000 tonnes
Substance Type
SUBSTANCE; GROUP
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)

EU CosIng Annex Listing

European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.

Annex II — Prohibited
Ref: 875
(EC) 2009/1223
CMR: Carcinogenic Cat. 1B()

Expanded Jurisdictional Detail

Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.

SA Saudi SFDA (II - Prohibited)
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)

Additional Ingredient Properties

3 property records from structured ingredient metadata.

cost_pricing
{"cost_tier": "mid-range", "estimated_cost_per_kg_usd_low": "28", "estimated_cost_per_kg_usd_high": "50", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "low", "primary_source_region": "Europe", "bulk_discount_threshold_kg": "100", "seasonal_price_variation": "low", "commodity_or_specialty": "specialty", "substitute_ingredients": "Silicones, Hem…
lipid
{"cas_number": "90622-58-5", "lipid_class": "ester", "botanical_source": "synthetic/derived", "plant_part": "derived", "extraction_method": "refined", "fatty_acid_profile_main_pct": "hydrocarbon", "omega_classification": "saturated", "comedogenicity_rating_0_5": "0", "absorption_rate": "fast", "skin_feel": "dry", "spreadability": "excellent", "emollient_grade": "A_excellent", "primary_application"…
silicone
{"cas_number": "Not silicone", "silicone_class": "other", "molecular_weight_Da": "190.0", "viscosity_cSt": "1.8", "volatility": "volatile", "evaporation_rate_relative_to_D5": "3.5", "refractive_index": "1.43", "specific_gravity": "0.78", "flash_point_C": "45.0", "surface_tension_mN_m": "20.5", "spreading_coefficient": "5.8", "film_forming_ability": "moderate", "skin_feel": "light", "slip_and_glide…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-adhesive/cohesive Defoamer Diluent Fragrance Processing aids not otherwise specified Softener and conditioner Solvent Viscosity modifier
Regulatory List Membership (3)
EU Banned in Cosmetics IFRA Fragrance Transparency List EU CosIng Cosmetics Ingredient Database

Expert Verdict

Expert safety assessment and concern-level summary for C13-15 Alkane.

Regulatory Flags

eu_banned_cosmetics ifra_fragrance eu_cosing_listed

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to C13-15 Alkane by CAS number or substance name.

Studies
1
Lowest NOAEL
750 mg/kg bw/day
Highest NOAEL
750 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Known Synonyms

Hydrotreated middle distillate (petroleum) Distillates (petroleum), straight run middle, hydrotreated Amoco NT-45 process oil EINECS 265-148-2 UNII-114P5I43UJ

Chemical Function

Solvent Viscosity modifier Softener and conditioner Anti-adhesive/cohesive

Regulatory Lists

inert_ingredient; non_food_use; Pesticides banned; Europe; Personal care IFRA Transparency active_ingredient; Europe; Pesticides

Australian Status

AICIS status: listed

Frequently Asked Questions

Is C13-15 Alkane safe in cosmetics?

C13-15 Alkane has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is C13-15 Alkane allowed in the EU?

C13-15 Alkane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does C13-15 Alkane do in cosmetics?

C13-15 Alkane functions as: Emollient, Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 64742-46-7.

What is the NOAEL for C13-15 Alkane?

The NOAEL (No Observed Adverse Effect Level) for C13-15 Alkane is =750 mg/kg bw/day based on a subchronic study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is C13-15 Alkane used outside cosmetics?

C13-15 Alkane also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does C13-15 Alkane have different safety status in cosmetics vs industrial chemicals?

C13-15 Alkane is classified GHS Danger (H226, H304, H315, H332, H350, H411) in the chemicals database but is allowed in EU cosmetics.

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